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CD_(34)组化法在瘢痕微血管构筑中的应用研究 被引量:18

The Application of CD_(34) Histochemical Method in the Study of Micro-vascular Architecture of human Scar
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摘要 目的 :探讨瘢痕微血管构筑在瘢痕形成、发展及临床防治中的意义。方法 :利用CD3 4血管内皮细胞可靠标记显示瘢痕微血管构筑 ,以期研究不同类型的瘢痕 ,同一类型瘢痕的不同时期以及同一瘢痕内不同区域的微血管构筑间的差异。结果 :不同类型的瘢痕间、瘢痕内不同区域及不同时期间瘢痕微血管密度均有明显统计学差异 ( p <0 .01 )。结论 :增生性瘢痕内的微血管密度明显高于萎缩性瘢痕的微血管密度 ;瘢痕早期微血管密度高随着病程延长而逐渐减少 ;瘢痕交界处为较幼稚瘢痕 ,血管最为丰富 ,能代表整个瘢痕的生物学行为。因此可把此区作为研究瘢痕发生、发展与转归的重点。 WT9.,10.25BZ]Objective:To explore the clinical significance of human scar micro-vascular architecture in the formation, development and prevention and treatment of scar. Method: CD34 antibody staining method was used to study the micro-vascular architecture of human scars. Results: Micro vascular density of hyperplastic scar in the central area was higher than that in the peripheral area; micro-vascular density of hyperplastic scar was higher than that of atrophic scar; Scars of different periods had different micro-vascular density. (P,0.01). Conclusion: In the border of the scar, the micro-vascular density is the highest. There scar border is the focal area to be studied in order to make clear the course of the generation, development and the fate of the scars. [
出处 《中国烧伤创疡杂志》 2000年第1期13-15,共3页 The Chinese Journal of Burns Wounds & Surface Ulcers
关键词 瘢痕 CD34组化法 微血管构筑 应用 Scar micro-vascular architecture
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参考文献2

  • 1戎广亚,田中.微血管形态学研究的常用方法及评价[J].中国病理生理杂志,1988,4(4):247-249.
  • 2[3]Hollingsworth H,Kohn E,Steinberg S,et al.Tumor angiogenesis in advanced stagy ovarian carcinoma.Am J Pathol,1995;147:33~41

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