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自体富血小板纤维蛋白治疗重度慢性牙周炎临床效果观察 被引量：6

Clinical effect of autologous platelet-rich fibrin in the treatment of severe chronic periodontitis
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摘要 目的观察自体富血小板纤维蛋白(PRF)用于重度慢性牙周炎手术治疗中的临床效果。方法选择2009年1月至2011年8月需要进行翻瓣术的重度慢性牙周炎患者18例(18颗患牙),分为试验组和对照组各9例。行常规翻瓣术,将PRF植入牙周组织缺损处(试验组)或仅行翻瓣术(对照组),术前及术后4个月测量探诊深度(PD)与临床附着水平(CAL)。结果两组各自术前与术后4个月的PD和CAL值比较,差异均有统计学意义(P<0.05)。试验组术前、术后的PD和CAL差值分别与对照组比较,差异均有统计学意义(P<0.05)。结论将PRF用于重度慢性牙周炎手术治疗中,可促进患牙牙周组织修复、改善牙周状况。
作者 程福新 王文玲
机构地区 福建省南平市第一医院口腔科
出处 《中国实用口腔科杂志》 CAS 2011年第12期750-751,共2页 Chinese Journal of Practical Stomatology
关键词 富血小板纤维蛋白 探诊深度 临床附着水平 慢性牙周炎 platelet-rich fibrin probing depth clinical attachment level chronic periodontitis
分类号 R78 [医药卫生—口腔医学]
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参考文献10

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同被引文献80

  • 1周延民,李琦,储顺礼,李春艳,王宇.即刻种植间隙充填富血小板纤维蛋白修复骨缺损2例[J].中国实用口腔科杂志,2009,2(8):504-505. 被引量：27
  • 2刘卫平,宋光保,周磊.种植技术在自体牙移植的临床应用研究[J].中国口腔种植学杂志,2006,11(1):33-36. 被引量：12
  • 3陈志方,丁晓红,黄忠锁,张晏更,郝新河.拔牙同期自体牙即刻移植的临床研究[J].口腔颌面外科杂志,2007,17(2):170-172. 被引量：4
  • 4Choukroun J, Adda F, Schoeffler C, et al. Une opportunit6 enparo- implantolo- gie: le PRF. lmplantodontie, 2001, 42 : 55 - 62.
  • 5Dohan DM, Choukroun J, Diss A, et al. Platelet - rich fibrin (PRF) : a second - generation platelet concentrate. Part I : technological concepts and evolution. Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 2006, 101(3) :e37 -e44.
  • 6Dohan Ehrenfest DM, Del Corso M, Diss A, etal. Three - dimensional architec- ture and cell composition of a Cbouk- roun' s platelet -rich fibrin clot and membrane. J Periodontol, 2010, 81 (4) :546 -555.
  • 7Dohan DM, Choukroun J, Diss A, et al.Platelet- rich fibrin (PRF): a second - generation platelet concentrate. Part Ⅱ: platelet- related biologic features. Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 2006, 101 (3) : e45 - eS0.
  • 8Lundquist R, Dziegiel MH, Agren MS. Bioactivity and stability of endogenous fi- brogenic factors in platelet - rich fibrin. Wound Repair Regen, 2008, 16 (3) : 356 - 363.
  • 9Dohan DM, Choukroun J, Diss A, et al. Platelet - rich fibrin (PRF) : a second - generation platelet concentrate. Part Ⅲ: leucocyte activation: a new feature for platelet concentrates? Oral Surg Oral Med Oral Pathol Oral Radial Endod, 2006, 101(3) :e51 -e55.
  • 10Tonelli P, Mannelli D, Brancato L, et al. Counting of platelet derived growth factor and transforming growth factor - beta in platelet - rich - plasma used in jaw bone regeneration. Minerva Stomatol, 2005, 54(1 -2) :23 -34.

引证文献6

二级引证文献29

中国实用口腔科杂志
2011年 第12期

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