摘要
目的:建立同时测定小儿至宝丸中可溶性砷、汞含量的方法。方法:采用人工胃液37℃振荡提取-原子荧光光谱测定小儿至宝丸中可溶性砷汞的含量。结果:砷在2～20 ng.mL-1之间,汞在2～10 ng.mL-1之间有良好的线性关系。回归方程为砷:I=38.139 2C-12.192 7,r=0.999 7;汞:I=582.628 6C+22.983 8,r=0.999 6。可溶性砷平均回收率为97.89%,RSD=1.50%;可溶性汞平均回收率为97.07%,RSD=1.59%。结论:本方法简便、可靠、准确,专属性强,可作为小儿至宝丸质量控制的方法。
Objective To establish a method for the content determination of dissolvable arsenic and dissolvable mercury in xiao- erzhibao pills. Methods ： Atomic Fluorescence Spectroscopy. Results ： The linear range of As was 2 - 20 ng ·mL^-1 （ r = 0. 999 7 ） , the average recovery was 97. 89% with RSD1.50% ; The linear range of Hg was 2 - 10 ng·mL^-l （ r = 0. 999 6 ） , the average recovery was 97.07% with RSD1.59%. Conclusion： The methods are stable and reliable and can be used in determination of dissolvable arsenic and dissolvable mercury in xiaoerzhibao pills.
出处
《中国药品标准》
CAS
2011年第6期433-435,共3页
Drug Standards of China
基金
兰州市科技计划支持项目(编号2010-1-165)
关键词
小儿至宝丸
可溶性砷
可溶性汞
原子荧光光谱法
Xiaoerzhibao Pills
Dissolvable arsenic
Dissolvable Mercury
Atomic Fluorescence Spectroscopy
