摘要
目的:了解梧州市药品不良反应(ADR)发生的特点及规律,为临床合理用药及ADR的监测和预防提供参考。方法:通过"全国药品不良反应监测网络"报告系统,以Excel电子表格的形式下载2010年梧州市ADR报告1 078例,并利用Excel表格统计和手工筛选方法,对有关数据进行分类统计及分析、评价。结果:1 078例ADR中,440例由抗菌药物引起(占39.36%);其次是中药制剂,有166例(占14.85%),ADR累及器官和(或)系统主要为皮肤及其附件(632例)。静脉滴注最容易导致ADR,有762例(占70.69%)。严重的ADR有54例。结论:临床应重视对引发严重的ADR和ADR发生频率高的药品的监测与分析。
OBJECTIVE：To investigate the regularity and characteristics of adverse drug reaction（ADR） occurred in Wuzhou city to provide reference for clinical rational drug use,ADR monitoring and prevention.METHODS： 1 078 ADR cases were downloaded from National ADR monitoring network reporting system using Excel.The ADR cases were statistically analyzed and evaluated by using Excel and manual selection.RESULTS： Of a total of 1 078 ADR cases,440（39.36%） were induced by anti-infective agents and 166（14.85%） by traditional Chinese medicine.Skin and its appendants（632 cases） were the major organs and（or） systems involved in ADR.762（70.69%） were caused by intravenous administration.There were 54 severe ADR cases.CONCLUSION： Great importance should be attached to monitoring and analysis of those drugs likely to induce severe ADR or those with high ADR frequency.
出处
《中国医院用药评价与分析》
2011年第12期1137-1140,共4页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
药品不良反应
报告
分析
Adverse drug reaction
Report
Analysis
