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少突胶质细胞肿瘤染色体1p／19q杂合性缺失检测及其临床意义 被引量：3

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摘要 少突胶质细胞肿瘤是起源于少突胶质细胞的肿瘤，约占颅内肿瘤的4％～5％。少突胶质细胞肿瘤病例50％～80％出现染色体1p／19q杂合性缺失。国内相关文献报道较少。
作者 李俊芝 冯晨 马遇庆 崔文丽 蒋茂芬 张巍
机构地区 新疆医科大学第一附属医院病理科 新疆乌鲁木齐市友谊医院理科 浙江省宁波市北伦区宗瑞医院病理科
出处 《中华实验外科杂志》 CAS CSCD 北大核心 2012年第1期139-139,共1页 Chinese Journal of Experimental Surgery
关键词 胶质细胞肿瘤 杂合性缺失 染色体 临床意义 少突胶质细胞 检测 颅内肿瘤 肿瘤病例
分类号 R73 [医药卫生—肿瘤]
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参考文献5

二级参考文献35

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  • 2张淑坤,卢德宏,朴月善,蔡彦宁,徐庆中.即时荧光定量PCR微卫星分析技术检测少突胶质细胞肿瘤染色体1p/19q杂合性缺失[J].中华病理学杂志,2006,35(12):731-734. 被引量：9
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共引文献27

同被引文献41

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  • 3Kanncr AA, Staugaitis SM, Castilla EA, et al. The impact of genotype on outcome in oligodendroglioma:validation of the loss of chromosome arm lp as an important factor in clinical decision making. J Neuro- surg, 2006,104 : 542-550.
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  • 10Huang L, Jiang T, Yuan F, et al. Correlation of chromosomes I p and 19q status and expressions of O6-methylguanine DNA methyltrans- ferase (MGMT),p53 and Ki-67 in diffuse gliomas of World Health Organization (WHO) grades II and III: a clinicopathological study. Neuropathol Appl Neurobiol,2009,35:367-379.

二级引证文献6

中华实验外科杂志
2012年 第1期

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