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提高经鼻给药效率的研究进展 被引量:4

Advances in improving the efficiency of nasal delivery
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摘要 目前,经鼻给药研究已进入临床试验阶段。近年来,对于如何提高经鼻给药的效率进行了大量研究。文章就一些影响经鼻给药靶向性和中枢神经系统药物浓度的因素进行了简要综述。 At present, intranasal delivery has entered clinical trial stage. In recent years, how to improving the efficiency of intranasal delivery has been extensively investigated. This article briefly reviews some factors that impact the targeting of intranasal delivery and the drug concentration in the central nervous system.
机构地区 南京大学医学院
出处 《国际脑血管病杂志》 北大核心 2011年第11期872-875,共4页 International Journal of Cerebrovascular Diseases
基金 基金项目:南京军区“十一五”课题(08MA097) 国家自然科学基金(30870848) 南京总医院医学科研课题(2009Q004)
关键词 投药 鼻内 药物释放系统 生物利用度 嗅通路 组织分布 Administration, intranasal Drug delivery systems Biological availability Olfactory pathways Tissue distribution
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