期刊文献+

TNF-α刺激下RNA结合蛋白HuR在大鼠心脏成纤维细胞中的表达变化 被引量:1

原文传递
导出
摘要 在心脏成纤维细胞(cardiac fibroblasts,CFs)中,炎症信号通路的持续活化,尤其是肿瘤坏死因子α(tumor necrosis factor-α,TNF-α)依赖的分子信号通路的激活介导了细胞一系列的病理变化[1~3],但其详细的机制尚不完全清楚,
出处 《心脏杂志》 CAS 2011年第6期820-821,826,共3页 Chinese Heart Journal
  • 相关文献

参考文献8

  • 1Gupta S,Das B,Sen S.Cardiac Hypertrophy:Mechanisms and Therapeutic Opportunities[J].Antioxid Redox Signal,2007,9(6):623-652.
  • 2Bozkurt B,Kribbs SB,Clubb FJ Jr,et al.Pathophysiologically relevant concentrations of tumor necrosis factor- promote progressive left ventricular dysfunction and remodeling in rats[J].Circulation,1998,97(14):1382-1391.
  • 3Turner NA,Mughal RS,Warburton P,et al.Mechanism of TNFal pha-induced IL-1alpha,IL-1beta and IL-6 expression in human cardiac fibroblasts:effects of statins and thiazolidinediones[J].Cardiovasc Res,2007,76(1):81-90.
  • 4Hinman MN,Lou H. Diverse molecular functions of Hu proteins[J].Cell Mol Life Sci,2008,65(20):3168-3181.
  • 5Bowers SL,Banerjee I,Baudino TA.The extracellular matrix:at the center of it all[J].J Mol Cell Cardiol,2010,48(3):474-482.
  • 6张杰,杨国栋,卢兹凡.肿瘤坏死因子α对新生大鼠心肌成纤维细胞增殖的影响及其机制[J].心脏杂志,2009,21(5):621-624. 被引量:1
  • 7Souders CA,Bowers SL,Baudino TA.Cardiac Fibroblast:The Renaissance Cell[J].Circ Res,2009,105(12):1164-1176.
  • 8Lafarga V,Cuadrado A,Lopez de Silanes I,et al.p38 Mitogen-activated protein kinase- and HuR-dependent stabilization of p21(Cip1) mRNA mediates the G(1)/S checkpoint[J].Mol Cell Biol,2009,29(16):4341-4351.

二级参考文献9

  • 1Buja LM, Vela D. Cardiomyoeyte death and renewal in the normal and diseased heart [ J ]. Cardiovasc Pathol, 2008, 17 ( 6 ) : 349 - 374.
  • 2Frangogiannis NG. The immune system and cardiac repair[ J]. Pharmacol Res, 2008, 58(2):88- 111.
  • 3Simpson P, Savlon S. Differentiation of rat myocytes in sitagle cell cultures with and without proliferating nonmyocardial cells [ J ]. Circ Res, 1982, 50(1) :101 -116.
  • 4Bujak M, Dobaczewski M, Chatila K, et al. Interleukin-1 receptor type I signaling critically regulates infarct healing and cardiac remodeling[J]. Am J Pathol, 2008, 173(1) :57 -67.
  • 5Jugdutt BI. Limiting fibrosis after myocardial infarction [ J ]. N Engl J Med, 2009, 360(15) :1567 - 1569.
  • 6Monden Y, Kubota T, Inoue T, et al. Tumor necrosis factor-alpha is toxic via reeeptor 1 and protective via receptor 2 in a murine model of myocardial infarction [ J ]. Ant J Physiol Heart Circ Physiol, 2007, 293 ( 1 ) : H743 - H753.
  • 7Jacobs M. , Staufenberger S, Gergs U, et al. Tumor necrosis factoralpha at acute myocardial infarction in rats and effects on cardiac fibroblasts[ J]. J Mol Cell Cardiol, 1999, 31 ( 11 ) :1949 - 1959.
  • 8Venkatachalam K, Venkatesan B, Valente AJ, et al. Wisp1, a promitogenic, pro-survival factor, mediates TNF-alpha stimulated cardiac fibroblast proliferation, but inhibits TNF-alpha-induced cardiomyocyte death [ J ]. J Biol Chem, 2009, 284 ( 21 ) : 14414 - 14427.
  • 9沈雁,严世芸.强心饮对肿瘤坏死因子α诱导的大鼠心肌成纤维细胞增殖和胶原合成以及激活蛋白1 mRNA表达的影响[J].中西医结合学报,2008,6(9):946-951. 被引量:5

同被引文献3

引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部