摘要
目的:研究睡宁胶囊的镇静催眠作用。方法:观察睡宁胶囊对小鼠自发活动、戊巴比妥钠小鼠睡眠时间和小鼠神经运动性电惊厥的影响。结果:睡宁胶囊能显著抑制小鼠自发活动,同时有协同戊巴比妥钠作用和明显对抗小鼠"精神运动性"电惊厥发作的作用。结论:睡宁胶囊有显著的镇静催眠作用,可以用来治疗失眠。
Objective: To study the sedative-hypnotic effect of Shuining capsules. Method: The effects of Shuining capsules on mice spontaneous activity, sleep time of mice injected pentobarbital sodium and mice nerve motility electric convulsion were observed. Result: Shuining capsules could significantly inhibit mice spontaneous activity. They had synergistic effect on pentobarbital sodium and inhibition effect on mice nerve motility electric convulsion. Conclusion: Shuining capsules show significant sedative hypnotic effect and may be appIied in the treatment of insomnia.
出处
《中国药师》
CAS
2011年第11期1605-1606,共2页
China Pharmacist
关键词
睡宁胶囊
镇静催眠
自主活动
戊巴比妥钠
电惊厥
Shuining capsules
Sedative hypnosis
Spontaneous activity
Pentobarbital sodium
Electric convulsion