摘要
目的探讨综合治疗恶性肠梗阻对改善生活质量、延长生存期的作用。方法选择2005年5月至2009年5月住院治疗的恶性肠梗阻患者29例,给予外科手术治疗或以生长抑素、静脉营养、止吐止痛等综合治疗,比较治疗前后肠梗阻症状、血生化指标、生活质量评分改善情况。结果29例患者梗阻完全缓解恢复至进食达68.97%;生活质量明显改善,治疗后患者生存质量卡氏评分(KPS评分)为(57±3)分,较治疗前(33±6)分明显升高(P<0.05);中位生存期为79 d。结论对恶性肠梗阻的综合治疗,能明显改善患者的临床症状和生活质量。
Objective To investigate the efficacy of comprehensive therapy for improving the quality of life and prolonging the survival period in treating malignant bowel obstruction（MBO）.Methods From May 2005 to May 2009,29 inpatients with MBO received surgical treatment or comprehensive therapy including somatostatin,total parenteral nutrition,antiemetics and odynolysis.The symptoms of bowel obstruction,biochemical indexes and life quality scores were compared before and after treatment.Results Obstruction was totally alleviated and recovered taking food in 20 cases（68.97%）,and the life quality was significantly improved.The Karnofsky scores after treatment were 57±3 and obviously higher than 33±6 before treatment（P 0.05）.The median survival period was 79 d.Conclusion The comprehensive therapy for MBO can obviously improve clinical symptoms and quality of life.
出处
《中国药业》
CAS
2011年第23期86-87,共2页
China Pharmaceuticals
关键词
恶性肠梗阻
晚期肿瘤
综合治疗
malignant bowel obstruction
advance cancer
comprehensive therapy
