摘要
观察金花葵总黄酮对糖尿病模型小鼠脂代谢以及SOD的影响,将链脲佐菌素(STZ)诱导成功的糖尿病小鼠模型随机分为正常对照组、金花葵黄酮高剂量组,中剂量组和低剂量组,阴性对照组和阳性对照组。灌胃4周后检测血脂和超氧化物岐化酶(SOD)的变化。结果表明,与阴性对照组相比,金花葵黄酮干预小鼠总胆固醇下降(P<0.01),高密度脂蛋白胆固醇上升(P<0.05),SOD上升(P<0.01)。适量金花葵黄酮对糖尿病小鼠脂代谢紊乱具有改善作用,并可以提高其体内SOD活性。
To explore effect of Abelmoschus manihot flavone （AMF） on blood lipids and SOD on diabetic mice,the diabetic mice model was made,the mice were divided randomly into 5 groups according to the blood glucose：normal control group,blood glucose positive control group,flavone high-dose,middle-dose,low-dose group.The level of blood lipid and SOD index were observed.Results showed that：in diabetic group,the blood lipid was significantly increased in comparison with control group.One dose of AMF could significantly increase SOD and HDL-c,at the same time,the TC was significantly decreased.AMF could effectively correct the discord of lipid metabolism and improve antioxidation ability invivo in diabetic.
出处
《中国农学通报》
CSCD
北大核心
2011年第29期102-106,共5页
Chinese Agricultural Science Bulletin
