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EPOCH方案治疗血管免疫母细胞性T细胞淋巴瘤 被引量:2

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摘要 目的观察EPOCH方案治疗血管免疫母细胞性T细胞淋巴瘤(A1TL)的疗效和毒副反应。方法经病理确诊为A1TL 14例,均采用EPOCH方案化疗,依托泊苷50mg·m2表柔比星12mg·m2,长春新碱O.4mg·m2,溶解于生理盐水500mL持续静滴24h,第一~四天;环磷酰胺750mg·m2,静脉推注.第六天;强地松60mg·m2,口服,第一~六天,21天为1周期。结果14例中CR5例(35.7%),PR4例(28.6%),总有效率64.2%,全组中位生存期20个月,2年总生存率为42.1%。主要不良反应为骨髓抑制。结论EPOCH方案治疗AITL疗效较好,患者容易耐受,毒副反应较少,值得临床进一步研究。
出处 《海峡药学》 2011年第10期93-94,共2页 Strait Pharmaceutical Journal
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