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上海地区变应性鼻炎患儿主要变应原的临床研究 被引量:7

Variability analysis of allergic rhinitis related allergens in children
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摘要 目的了解近年来上海地区变应性鼻炎患儿的变应原特征,为儿童变应性鼻炎的防治提供临床依据。方法 2005年6月~2010年5月间,对上海地区拟诊变应性鼻炎的儿童行皮肤点刺试验(SPT),分析检测结果 ,并探讨了阳性病例在性别、年龄、检测的年份及季节等方面的差异性。结果 646例患儿中SPT阳性率81.73%,变应原分布以屋尘螨、粉尘螨为主;阳性病例在性别及检测年、月份分布上的差异无统计学意义(P>0.05);年龄较小组(3~5岁组)的SPT阳性率较低(P<0.05)。结论尘螨为上海地区变应性鼻炎患儿的的主要变应原,致敏阳性率常年维持较高水平,提示了加强尘螨的长期管理在防治儿童变应性鼻炎方面的重要意义。 Objective To determine the features of allergens in children with allergic rhinitis during the recent 5 years of Shanghai, and provide clinical reference for local management strategies. Methods Children with primary diagnosis of allergic rhinitis in shanghai area were given skin prick test (SPT) fi'om June, 2005 to May, 2010. The positive rates were calculated and further analysed in regarding to age, gender, testing months, Results Among 646 children, the total positive rate of SPT was 81.73%. Dermatophagoides farinae (Der. f) and Dermatophagoides pteronyssinus (Der. p) were identified as the mostly responsible allergens. Among the positive subjects, the younger group showed a lower SPT positive rate than the elder (P〈0.05), but no significant difference was found between the gender, years, or testing months (all, P〉0.05). Condusion Dust mite was the most common allergen in children with allergic rhinitis in Shanghai area, and its sensitization rate sustained constantly a high level around the year, suggesting the importance of long-term mite control during the management of children with allergic rhinitis in Shanghai area.
出处 《中国中西医结合耳鼻咽喉科杂志》 2011年第5期339-342,共4页 Chinese Journal of Otorhinolaryngology in Integrative Medicine
关键词 变应性鼻炎 变应原 儿童 皮肤点刺试验 allergic rhinitis allergen child skin prick test
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