期刊文献+

IVF-ET与胎盘血管病变的相关性研究

原文传递
导出
摘要 随着IVF-ET的广泛开展,其妊娠并发症和子代健康状况也受到越来越多的关注。胎盘血管发育异常会导致前置胎盘、妊娠期高血压疾病、低出生体质量等妊娠并发症和不良产科结局。关于IVF-ET与胎盘血管发育异常相关疾病的关联性说法不一。亲代的不孕背景及IVF-ET过程中非生理性干预进一步导致的孕妇体内激素水平紊乱均有可能改变胚胎的早期发育,从而在妊娠后期出现并发症并影响子代健康。目前公认的IVF可能导致的妊娠期并发症及不良妊娠结局包括:妊娠期高血压、前置胎盘、低体质量儿、超低体质量儿等,这些不良结局的产生大多是与胎盘发育障碍,尤其与胎盘血管发育异常相关。亲代不孕背景、IVF-ET的不当操作、促排卵所致激素水平紊乱都会影响早期胎盘血管发生,其涉及的功能障碍以及蛋白、基因表达改变情况,还需进一步的实验室研究。
出处 《生殖与避孕》 CAS CSCD 北大核心 2011年第10期695-699,共5页 Reproduction and Contraception
  • 相关文献

参考文献15

  • 1焦蕊丽.体外受精-胚胎移植足月妊娠胎盘中表皮生长因子受体的表达及其形态学变化.河北:河北医科大学,2004.
  • 2马黔红.辅助生殖技术与前置胎盘[J].实用妇产科杂志,2009,25(10):585-586. 被引量:10
  • 3Pregnancies and births resulting from in vitro fertilization French national registry, analysis of data 1986 to 1990 FIVNAT (French In Vitro National). Fertil Steril, 1995, 64(4) 746-56.
  • 4Sutcliffe AG, Ludwig M. Outcome of assisted reproduction. Lancet, 2007, 370(9584):351-9.
  • 5Street ME, Seghini P, Fieni S, et al. Changes in interleukin-6 and IGF system and their relationships in placenta and cord blood in newborns with fetal growth restriction compared with controls. Eur J Endocrinol, 2006, 155(4):567-74.
  • 6张翠莲,乔玉环,谢娟珂,谷保霞,王娇锋,张静.胚胎移植日血清雌激素下降幅度对体外受精-胚胎移植结局的影响[J].生殖与避孕,2007,27(8):523-526. 被引量:16
  • 7Chung K, Coutifaris C, Chalian R, et al. Factors influencing adverse perinatal outcomes in pregnancies achieved through use of in vitro fertilization. Fertil Steril, 2006, 86(6): 1634-41.
  • 8周灿权,黄孙兴.浅析我国辅助生殖技术发展中的几个问题[J].广东医学,2010,31(19):2473-2474. 被引量:3
  • 9Wang JX, Clark AM, Kirby CA, et al. The obstetric outcome of singleton pregnancies following in vitro fertilization/gamete intra-fallopian transfer. Hum Reprod, 1994, 9(1):141-6.
  • 10Roy H, Bhardwaj S, Yla-Herttuala S. Biology of vascular endothelial growth factors. FEBS Lett, 2006, 580(12): 2879-87.

二级参考文献43

  • 1王慧焱,王玢,孙海翔,胡娅莉.不同黄体支持方法对体外受精-胚胎移植结果的影响[J].生殖与避孕,2004,24(4):222-225. 被引量:8
  • 2汤惠茹,李蓉,张青萍.阴道B超下子宫内膜形态与试管婴儿成功率的关系[J].放射学实践,2005,20(3):265-267. 被引量:23
  • 3张爱军,冯云,黄晓燕,孙贻娟,牛志宏,陆小溦.小于35岁助孕患者移植不同胚胎数的临床研究[J].生殖与避孕,2005,25(6):381-383. 被引量:4
  • 4de Geyter C, Schmitter M, de Geyter M, et al. Prospective evaluation of the ultrasound appearance of the endometrium in a cohort of 1 186 infertile women. Fertil Steril, 2000,73 (1):106-13.
  • 5Dietterich C, Check JH, Choe JK, et al. Increased endometrial thickness on the day of human chorionic gonadotropin injection does not adversely affect pregnancy or implantation rates following in vitro fertilization-embryo transfer. Fertil Steril, 2002, 77(4):781-6.
  • 6Schield RL, Knobloch C, Dora C, et al. Endometrial receptivity in an in vitro fertilization program as assessed by spiral artery blood flow, endometrial thickness, endomelrial volume, and uterine artery blood flow. Fertil Steril, 2001, 75(2):361-6.
  • 7Kovacs P, Matyas S, Boda K, et al. The effect of endometrial thickness on IVF/ICSI outcome. Hum Reprod, 2003, 18(11): 2 337-41.
  • 8Zhang XQ, Chen HH, Confino E, et al. Increased endometrial thickness is associated with improved treatment outcome for selected patients undergoing in vitro fertilization-embryo transfer. Fertil Steril, 2005, 83(2):336-40.
  • 9Kupesic S, Bekavac I, Bjelos D, et al. Assessment of endometrial receptivity by transvaginal color Doppler and three-dimensional power Doppler ultrasonography in patients undergoing in vitro fertilization procedures. J Ultrasound Med, 2001, 20(2): 125-34.
  • 10Quintero RB, Sharara FI, Milki AA. Successful pregnancies in the setting of exaggerated endometrial thickness. Fertil Steril, 2004, 82(1):215-7.

共引文献70

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部