摘要
血浆高同型半胱氨酸血症可引起妊娠期相关性疾病,如妊娠高血压、胎盘血管疾病、先天性心脏病、增加血小板黏附性和致妊娠丢失,严重者危及母子生命。补充叶酸、维生素B6和维生素B12有望降低妊娠相关疾病的发生,对于降低孕产妇及围产儿发病率及死亡率有重大意义。
The high maternal hyperhomocysteinemia can cause related disease during the pregnancy, even endanger the living life of mother and fetus. Aggravated diseases such as pregnancy hypertension and complications hypertersive disorder and pregnancy, placental vascuvar disease, congenital heart disease, platelet abnormalities and pregnancy loss and soon. With the progress of pregnancy, levels of serum folie acid, vitamin B6 and vitamin B12 gradually reduced till the late pregnancy, resulting in obstacles from plasma bomocysteine to methionine, and forming high hyperhomocysteinemia. Therefore, supplementary folic acid, vitamin B6 and vitamin B12 are expected to reduce the incidence of pregnancy-related diseases. It＇s significant to reduce maternal and perinatal morbidity and mortality.
出处
《中国慢性病预防与控制》
CAS
北大核心
2010年第1期104-106,共3页
Chinese Journal of Prevention and Control of Chronic Diseases
关键词
同型半胱氨酸
妊娠高血压病
妊娠期血小板异常
胎盘血管疾病
先天性心脏病
妊娠丢失
Homocysteine
Pregnancy-induced hypertension disease
Platelet abnormalities during pregnancy
Placental vascular disease
Congenital heart disease
Pregnancy loss.
