摘要
微小RNA(miRNA)在卵巢癌中表达明显改变。基于微阵列芯片检测的卵巢癌相关miRNA表达谱和后续的对个别miRNA的深入研究,发现其与卵巢癌的发生、发展、复发、耐药等密切相关,有望用于卵巢癌早期诊断、复发检测、预后判定及治疗。
The expression of microRNAs (miRNAs) alters obviously in ovarian cancer. Through miRNA profile based on a microarray platform and further research on individual one, they are found to be closely related to pathogenesis, progression, recurrence, and drug resistance of ovarian cancer and have a good prospect in applying it in the early diagnosis, detection recurrence, prognosis and therapy of ovarian cancer.
出处
《国际肿瘤学杂志》
CAS
2011年第10期790-793,共4页
Journal of International Oncology
关键词
微RNAS
卵巢肿瘤
诊断
治疗
MicroRNAs
Ovarian neoplasms
Diagnosis
Therapy