摘要
目的:为无痛肠镜选择一个安全、操作性强的麻醉方法。方法:选择300例符合纳入标准的需作无痛肠镜的患者随机分成三组,单纯丙泊酚组(P组)、布托啡诺复合丙泊酚组(B组)、舒芬太尼复合丙泊酚组(S组),每组100例;P组先静脉注射0.9%生理盐水0.1ml/kg,3分钟后缓慢静注丙泊酚至意识消失,并使用丙泊酚维持麻醉;B组先静注布托啡诺0.1ml/kg(布托啡诺浓度为0.1mg/ml),3分钟后缓慢静注丙泊酚至意识消失,并使用丙泊酚维持麻醉;S组先缓慢静注舒芬太尼0.1ml/kg(舒芬太尼浓度为0.1μg/ml)3,分钟后缓慢静注丙泊酚至意识消失,并使用丙泊酚维持麻醉。结果:B组、S组镇痛效果、循环抑制、术后恢复时间明显优于P组,术中呼吸抑制三组间P组最明显、S组次之、B组最轻。结论:布托啡诺复合丙泊酚组在无痛肠镜检查的麻醉中更安全,更适用。
Objective：To select a safe and workable method of anesthesia for colonoscopy.Methods： 300 patients with the admitted criteria and requiring for the painless colonoscopy were randomly divided into three groups：propofol group（P group）,butorphanol plus propofol group（B group） and sufentanil plus propofol group（S group）.Every group has 100 patients.In P group,patients were firstly given intravenous injection of 0.9% saline,3 minutes later,intravenous injection of propofol 0.1ml/kg until losing the consciousness and then anesthesia was maintained with propofol;In Group B,patients were firstly given butorphanol 0.1ml/kg（consistence of butorphanol is 0.1mg/ml）,3 minutes later,intravenous injection of propofol until losing the consciousness and then anesthesia was maintained with propofol;In S group,patients were firstly given butorphanol 0.1ml/kg（consistence of sufentanil is 0.1ug/ml）,3 minutes later intravenous injection of propofol until losing the consciousness and then anesthesia was maintained with propofol.Results： Antinociceptive effects of B group and S group were significantly better than those of P group.Circulatory inhibition of B group and S group was significantly less serious than that of P group;Time of postoperative resuscitation of B group and S group was markedly shorter than that of P group;Respiratory inhibition during operation was the most common in groups P,followed by group S,which is the least serious in B group.Conclusion：Butorphanol plus propofol anesthesia in painless colonoscopy is safer and more applicable.
出处
《川北医学院学报》
CAS
2011年第5期432-434,共3页
Journal of North Sichuan Medical College
关键词
丙泊酚
布托啡诺
舒芬太尼
无痛肠镜麻醉
Propofol
Butorphanol
Sufentanil
Painless colonoscopy anesthesia
