摘要
目的观察布托啡诺复合丙泊酚用于门诊无痛胃镜的麻醉效果及安全性。方法门诊ASAⅠ～Ⅱ级无痛胃镜检查的患者60例,随机分为两组,各30例。PF组首次静推芬太尼1.0μg/kg+丙泊酚2.0 mg/kg,PB组首次静推布托啡诺20μg/kg+丙泊酚2.0 mg/kg,术中根据需要追加丙泊酚。记录麻醉前、意识消失时、苏醒时的平均动脉压(MAP)、心率(HR)、血氧饱和度(SPO2)变化及给药结束至睫毛反射消失时间和苏醒时间,观察术中呼吸抑制情况和麻醉效果分级。结果麻醉效果满意两组相比无差异,两组患者诱导后MAP、HR、SPO2均有所下降,与诱导前比较差异具有统计学意义(P<0.01),但两组之间比较差异无统计学意义(P>0.05),两组苏醒时间相比无差异(P>0.05),术中呼吸抑制PF组明显高于PB组(P<0.05)。结论布托啡诺复合丙泊酚用于无痛胃镜麻醉效果好且不良反应少,是一种理想的无痛胃镜麻醉方法。
Objective To observe the anesthesia effect and safety of butorphanol and propofol for outpatient painless endoscopy.Methods 60 patients,whose ASA Ⅰ~Ⅱ grad and adopted outpatient painless gastroscopy were randomly divided into two groups,each group were 30 cases.PF group first bolus of fentanyl 1.0 μg/kg＋propofol 2.0 mg/kg,PB group for the first time bolus butorphanol 20 μg/kg＋propofol 2.0 mg/kg,to the need for additional surgery in the propofol phenols.Recorded before anesthesia,loss of consciousness,awakening,when mean arterial pressure（MAP）,heart rate（HR）,oxygen saturation（SPO2） changes and delivery time between the end of eyelash reflex and recovery time,intraoperative circumstances and respiratory depression anesthesia levels.Results Satisfied with the results of anesthesia was no difference between the two groups,two groups of patients after induction of MAP,HR,SPO2 has declined,and induced a statistically significant difference between the former（P0.01）,but no statistical difference between the two groups significance（P0.05）,recovery time was no difference between the two groups（P0.05）,intraoperative respiratory depression PF group was significantly higher than the PB group（P0.05）.Conclusion butorphanol and propofol anesthesia for painless gastroscope are effective and less adverse reactions.It is an ideal method in painless endoscopy anesthesia.
出处
《黑龙江医学》
2011年第11期832-833,共2页
Heilongjiang Medical Journal
关键词
无痛胃镜
布托啡诺
丙泊酚
Painless gastroscope
Butorphanol
Propofol
