摘要
目的:通过97例肝硬化患者的胃镜检查,对上消化道黏膜病变程度与Child-Pugh分级的关系进行探讨。方法:将97例肝硬化患者根据Child-Pugh分级,分为A级、B级两组,观察其食管静脉曲张轻、中、重程度、门脉高压性胃病、溃疡、食管炎及十二指肠球炎发生率,并做统计学处理。结果:97例肝硬化患者食管静脉曲张检出率90.7%,门脉高压性胃病检出率54.6%,胃溃疡检出率17.5%,十二指肠溃疡检出率9.3%,十二指肠球炎检出率27.8%,反流性食管炎检出率10.3%。食管静脉曲张严重程度(χ2=10.95)和反流性食管炎发生率(χ2=6.12)与Child-Pugh级别呈正相关(P<0.01),而门脉高压性胃病、胃溃疡、十二指肠溃疡、十二指肠球炎发病率与之无明显关系(P均>0.05)。结论:肝硬化患者食管静脉曲张严重程度和反流性食管炎发生率随Child-Pugh分级而上升,门脉高压性胃病、胃溃疡、十二指肠溃疡、十二指肠球炎发病率则与Child-Pugh分级无明显关系。
Objective： To discuss the relationship between upper gastrointestinal mucosa coat lesion and hepatic function Child-Pugh grade through gastroscope in Ninety and seven patients with liver cirrhosis. Methods ： Ninety-seven patients of liver cirrhosis were divided into A group and B group based on the hepatic function Child-Pugh grade, observed the incidence rate of esophageal varices, portal hypertensive gastropathy, ulcer, esophagitis and duodenitis, then compiled statistics. Results： The esophageal varices rate were about 90.7%, portal hypertensive gastropathy rate were about 54. 6%, gastric ulcer rate were 17.5%, duodenal ulcer rate were 9. 3%, duodenal rate were 27. 8%, while gastroesophageal reflux disease rate were 10. 3% The incidence rate of esophageal varices was increased with the increased grade of Child-Pugh grade （ X^2 = 10. 95, P 〈 0. 01 ） While, the incidence rate of gastroesophageal reflux disease was increased with the increased grade of Child-Pugh grade （ X^2 = 6. 12, P 〈 0.01 ） . In addition, the prevalence of portal hypertensive gastropathy , ulcer, duodenitis was not significantly different between A and B groups （ P 〉 0. 05 ） . Conclusion ： There is a positive correlation between Child-Pugh grade and the degree of esophageal varices, gastroesophageal reflux disease, while no correlation show between Child-Pugh score and portal hypertensive gastropathy, gastric ulcer, duodenal ulcer, duodenitis.
出处
《中西医结合肝病杂志》
CAS
2011年第5期278-279,281,共3页
Chinese Journal of Integrated Traditional and Western Medicine on Liver Diseases
