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坦索罗辛在体外冲击波碎石后的临床应用 被引量:2

Clinical application of tamsulosin in the patients after extracorporeal shock wave lithotripsy
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摘要 目的观察体外冲击波碎石(ESWL)治疗输尿管中下段结石后,应用坦索罗辛辅助治疗的效果。方法对2009-12~2010-07 510例输尿管中下段结石行ESWL后的患者,采用双盲对比法分两组进行对比治疗观察,其中实验组(226例)在对照组(284例)治疗的基础上加用坦索罗辛。观察时间为20 d。结果实验组结石排净率为84.5%(191/226),对照组结石排净率为62.3%(177/284),实验组的排净率明显高于对照组(P<0.01)。结论坦索罗辛组与对照组比较,排净率明显提高,复碎率及碎后再次肾绞痛发生率明显降低,药物副作用少、症状轻。 Objective To observe the effect of tamsulosin in the adjuvant therapy after the extracorporeal shock wave lithotripsy (ESWL) in the patients with middle and lower ureteral calculi. Methods From December 2009 to July 2010,after ESWL, 510 patients with middle-lower ureteral calculi were divided into two groups: the experimental group and the control group. The experiment was conducted by double-blind method. And the experiment group was added tamsulosin based on the control group. The observation lasted for 20 days. Results The stone-free rate of the experimental group was 84. 5% ( 191/226), that of the control group was 62. 3% (177/284). The stone- free rate of the experimental group was significantly higher than that of the control group( P 〈 0. 01 ). Conclusion Compared with the control group, the stone-free rate of the tamsulosin group significantly increased, the re-broken incidence and the renal colic incidence after broken stone significantly reduced, with fewer side effects, and mild symptoms.
作者 庞业小 廖康
出处 《中国临床新医学》 2011年第8期709-711,共3页 CHINESE JOURNAL OF NEW CLINICAL MEDICINE
基金 贵港市科学研究与技术开发攻关项目(编号:贵科攻0916001)
关键词 体外冲击波碎石 中下段输尿管结石 坦索罗辛 Extracorporeal shock wave lithotripsy(ESWL) Middle and lower ureteral calculi Tamsulosin
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参考文献5

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共引文献15

同被引文献17

  • 1伍杏容.体外冲击波碎石术病人的整体护理[J].基层医学论坛,2006,10(7):643-644. 被引量:1
  • 2权伟合,吴振启,李虎宜,梁志恒,王凉梅.α_1受体阻滞剂辅助治疗提高ESWL后上尿路结石清除率[J].临床泌尿外科杂志,2007,22(3):210-212. 被引量:7
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  • 9Dellabella M, Milamese G, Muzzonigro G. Randomized trial of the efficacy of tamsulosin, nifedipine and phloroglucinol in medi- Cal expulsire therapy for distal ureteral calculi[J]. J Urol, 2005,174 (1):167-172.
  • 10涂传仕,魏世杰,崔奇,等.坦索罗辛辅助ESWL治疗上尿路结石的临床研究[J].中外健康文摘,2011,8(10):189-190.

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