摘要
目的探讨血清中神经元特异性烯醇化酶(NSE)、细胞角蛋白19片段(CYFRA21-1)和糖类抗原19-9(CA19-9)的水平变化对肺癌的诊断价值。方法采用化学发光法对112例肺癌患者、68例肺良性疾病患者和50例健康人血清中的NSE、CY-FRA21-1和CA19-9含量进行检测及比较。结果肺癌组的三种血清肿瘤标志物水平均明显高于肺良性疾病患者组和正常对照组,差异均有统计学意义(P<0.01)。三种肿瘤标志物联合检测敏感性高达82.1%,准确度达90.0%,高于单项检测。结论三项肿瘤标志物联合检测可提高肺癌诊断的敏感性和准确性。
Objective To explore the Diagnostic value of combined detection in serum NSE,CYFRA21-1 and CA19-9 levels for hung cancer.Methods Technique of electrochemiluminescence immunoassay was used to measure the serum NSE,CYFRA21-1 and CA19-9 levels in 112 patients with lung cancer,68 patients with benige lung diseases and 50 normal controls.Results The levels of NSE,CYFRA21-1 and CA19-9 in lung cancer group were significantly higher than those in benign lung diseases and normal control groups（P0.01）.Three tumor markers positive rate as high as 82.1%,accuracy was 90.0%,higher than the single test.Conclusion Three tumor markers of combined detection for lung cancer can improve the sensitivity and accuracy.
出处
《中外医学研究》
2011年第22期51-52,共2页
CHINESE AND FOREIGN MEDICAL RESEARCH
