摘要
目的:了解我院药品不良反应(ADR)发生的特点及引发ADR的相关因素,促进临床合理用药。方法:对我院2006～2010年收集的303例ADR报告进行回顾性分析。结果:303例ADR报告中,各年龄段均有分布,50岁以上的患者较多;给药途径以静脉给药为主,共235例(77.6%);抗微生物药139例(38.7%),其次是中药制剂58例(16.2%);皮肤及附件损害最多,有108例(28.7%)。结论:ADR发生与多种因素有关,应积极开展ADR监测工作,以减少或避免ADR的发生。
Objective ：To investigate the features and the relevant factors of adverse drug reactions （ADR）occurring in our hospital so as to promote rational clinical drug use. Method：303 cases of ADR reports collected in our hospital from 2006 to 2010 were statistically analyzed. Result：The 303 cases occurred in different age group but more often in aged people. 235 cases （77.6%） were caused by administration of intravenous injection; 139 cases（38.7% ） were antimicrobial,58 cases （ 16.2% ） were traditional Chinese medicine （TCM） preparation ; 108 cases （ 28.7% ） presented with lesions of skin and appendages. Conclusion： ADR is associated with a variety of factors. It is advisable to tighten ADR monitoring so as reduce or avoid occurrence of ADR.
出处
《药物流行病学杂志》
CAS
2011年第7期348-350,共3页
Chinese Journal of Pharmacoepidemiology
关键词
药品不良反应
报告
合理用药
Adverse drug reactions
Report
Rational drug use
