摘要
以环氧乙烷、CO和甲醇为原料,Co2(CO)8为催化剂,合成了3-羟基丙酸甲酯,并考察了不同配体、压力、温度和时间对环氧乙烷氢酯基化合成3-羟基丙酸甲酯反应的影响。得出了最佳工艺条件为:以3-羟基吡啶为配体,压力7.5MPa,温度75℃,时间4 h。在此条件下,3-羟基丙酸甲酯的收率和选择性分别为64.0%和95.7%。
Methyl 3-hydroxypropanoate was prepared by hydroesterification of ethylene oxide with carbon monoxide in the presence of Co2（CO）8 catalyst and methanol.The effects of ligands,carbon monoxide pressure,reaction temperature and time on the yield and selectivity were investigated.When Co2（CO）8 liganded with 3-hydroxypyridine was used as catalyst,under 7.5MPa of carbon monoxide at 75 ℃ for 4 hours,the selectivity and yield of methyl 3-hydroxypropanoate were 95.7% and 64.0%,respectively.
出处
《天然气化工—C1化学与化工》
CAS
CSCD
北大核心
2011年第3期34-36,41,共4页
Natural Gas Chemical Industry
