摘要
目的:检测冠心病(CHD)患者血清超敏C-反应蛋白(hs-CRP)、纤维蛋白原(FIB)和D-二聚体(DD)水平,探讨其在CHD中的临床应用价值。方法:选择CHD患者86例,采用免疫比浊法定量测定hs-CRP和DD,凝血酶凝固时间法(Clauss法)定量测定FIB,并以30例健康对照进行比较。结果:①急性心肌梗死(AMI)组、不稳定型心绞痛组血清hs-CRP、FIB、DD水平均明显高于稳定型心绞痛(SA)组和对照组,差异有统计学意义(P<0.01);②SA组血清hs-CRP水平明显高于对照组,差异有统计学意义(P<0.01);③SA组FIB、DD水平与对照组相比差异无统计学意义(P>0.05)。结论:CHD患者血清hs-CRP、FIB和DD的检测能较好地反映CHD患者的病情程度,有重要的临床应用价值。
Objective：To investigate the value of clinical application in coronary heart disease（CHD） by measuring serum levels of high-sensitivity C-reactive protein（hs-CRP）,fibrinogen（FIB） and D-Dimer（DD） in patients with CHD.Method：The levels of hs-CRP and D-D in 86 patients with CHD were measured by turbidimetric immunoassay.The level of FIB was detected by Clauss.The 30 healthy cases regarded as controls.Result：①The serum levels of hs-CRP,FIB and D-D in patients with acute myocardial infarction（AMI） and unstable angina（UA） were higher than those in patients with stable angina（SA） and health controls significantly（P0.01）.②The serum level of hs-CRP in patients with SA was higher than those in health controls significantly（P0.01）.③The serum levels of FIB and D-D were no significant difference between SA and health controls（P0.05）.Conclusion：The serum levels of hs-CRP,FIB and D-D can preferably reflect the severe degree of CHD,and have very important clinical value.
出处
《临床心血管病杂志》
CAS
CSCD
北大核心
2011年第6期415-416,共2页
Journal of Clinical Cardiology
关键词
冠心病
C-反应蛋白
纤维蛋白原
D-二聚体
coronary disease
high-sensitivity C-reactive protein
fibrinogen
D-Dimer
