摘要
目的:了解心脏病孕妇新生儿的生长发育指标及合并症,探讨其影响因素。方法:2009年9月至2010年3月安贞医院产科441例新生儿,按孕妇是否合并心脏病分为心脏病组79例、对照组362例;同时按孕妇心脏病类型、心脏病孕妇心功能分级、心脏病孕妇孕期用药及心脏病合并肺动脉高压程度分组并进行组间比较。结果:1.心脏病组与对照组比较:剖宫产率(P<0.01)、平均出生身长(P<0.001)、平均出生体质量(P<0.001)、正常足月儿发生率(P<0.001)、出生低体质量儿发生率(P=0.001)、巨大儿发生率(P<0.05)及早产儿发生率(P<0.01)比较差异有统计学意义。2.孕妇不同心脏病类型的3组新生儿的正常足月儿发生率(P<0.01)、平均出生体质量(P<0.05)差异有统计学意义。3.心功能Ⅰ～Ⅱ组与Ⅲ～Ⅳ组新生儿的正常足月儿(P<0.001)、低出生体质量儿(P<0.001)、早产儿发生率(P<0.001)的差异有统计学意义。4.随着肺动脉高压程度的加重,早产儿、低出生体质量儿及窒息儿增加,正常足月儿减少。结论:心脏病心功能Ⅲ～Ⅳ和/或合并肺动脉高压孕妇的新生儿剖宫产率高,易发生出生低身长、出生低体质量及早产儿。
Objective：To research the growth and development and compliments of neonates in pregnant women with heart disease,and identify the influence factors.Methods： Four hundred and forty one neonates borned in our hospital between September 2009 and March 2010 were reviewed.They were divided into two groups according to whether their mothers had cardiac diseases： cardiac disease group（n =79） and control group（n = 362）;and they were divided into several groups according to the type of cardiac disease of their mothers’,the degree of New York heart association（NYHA） class of pregnant women with cardiac disease,medications used during pregnancy with cardiac disease,the degree of pulmonary hypertension complicated with cardiac disease.The neonatal outcomes were analyzed.Results： 1.Comparison between cardiac disease group and control group： cesarean section rate（P〈0.01）,average body length（P〈0.001）,average body weight（P〈0.001）,the rate of normal term infant（P〈0.001）,the rate of low birth weight infant（P =0.001）,the rate of macrosomic（P〈0.05）,the rate of preterm infant（P〈0.01）.2.The type of cardiac disease in pregnant women and neonatal outcomes： the rate of normal term infant（P〈0.01）,average body weight（P〈0.05） in these three groups.3.NYHA class and neonatal outcomes： comparison between classⅠ-Ⅱgroup and class Ⅲ-Ⅳ group,the rate of normal term infant（P〈0.001）,the rate of low birth weight infant（P〈0.001）,the rate of preterm infant（P〈0.001）.4.Pulmonary hypertension complicated with cardiac disease and neonatal outcomes： as the degree of pulmonary hypertension developed,the cases of class Ⅲ-Ⅳ,preterm infant,low birth weight infant and asphyxia more,the cases of normal term infant less,however.Conclusions： Overall,the neonates of pregnant women with cardiac disease have higher cesarean section rate,and are prone to lower birth length and lower birth weight.Pre-term delivery and low birth weight are the most common neonatal events especially when the NYHA class of preg-nant women are Ⅲ ～Ⅳ and/ or pulmonary hypertension are complicated.
出处
《心肺血管病杂志》
CAS
2011年第3期237-240,共4页
Journal of Cardiovascular and Pulmonary Diseases
关键词
心脏疾病
孕妇
新生儿
Heart diseases
Pregnancy associated
Neonatal
