摘要
目的 评价顺铂联合长春新碱及环磷酰胺（ 以下简称ＰＶＣ方案） 治疗上皮性卵巢癌的疗效。方法 回顾性分析我科自１９８７ 年１ 月至１９９３ 年５ 月联合化疗治疗８５ 例上皮性卵巢癌的近、远期疗效。结果 ４８ 例卵巢上皮癌应用ＰＶＣ方案化疗，近期疗效（ 有效率） 为６８．７５％ ，与其他化疗方案（３７ 例，有效率为４０．５％ ）比较差异有显著性（ Ｐ＜０．０２） 。远期疗效分析，ＰＶＣ化疗方案组１、５ 年生存率分别为９１．５％ 和４１．４％ ，与其他化疗方案比较差异有显著性（ Ｐ＜ ０．０１，Ｐ＜ ０．０２） 。本组无一例因化疗副反应或其并发症死亡。结论 ＰＶＣ方案化疗是治疗卵巢上皮癌的有效方案之一。
Objective To evaluate the effectiveness of combined chemotherapy of Cisplatin plus Vincristin and Cyclophosphamide (PVC) on the patients with epithelial ovarian cancer. Methods The chart and follow-up data of 85 patients treated with combined chemotherapy form Jan. 1987 to May 1993 in Shandong Tumor Hospital and Institute were reviewed. Their immediate treatment results, long-term follow-ups and side effects were retrospectively analysed. Results 48 patients with epithelial ovarian cancer were treated with PVC combined chemotherapy. Their clinlcal response rate was 68.75%. The other chemotherapy repimens were qiven to 37 patinents. There was a significant difference in the clinical response rate betwecn the two grous ( P <0 02). In the PVC group, the 1-,5-year survival rates were higher (91.5%,41.4%) than those in the control group ( P <0 01, P <0 02). None in the test group died of side effects or complication. Conclusions PVC combined chemotherapy may be one of the effective regimens in the treatment of epithelial ovarian cancer. [
出处
《河南肿瘤学杂志》
1999年第4期290-292,共3页
Henan Journal of Oncology
