摘要
目的：建立复方皂矾丸中西洋含量测定测方法。方法：采用高效液相色谱法同时测定西洋参中人参皂苷Rg1、人参皂苷Re和人参皂苷Rb。的含量。结果：高效液相色谱人参皂苷Rg1的线性范围是0．63—5．06μg（r=0．9999），平均加样回收率101．12％（RSD=2．14％），人参皂苷Re的线性范围是1．05～8．4μg（r=0．9998），平均加样回收率100．71％（RSD=1．57％），人参皂苷Rb1的线性范围是2．468～19．744μg（r=0．9997），平均加样回收率97．22％（RSD=1．92％）。结论：该方法操作简便、结果准确、重现性好，可用于复方皂矾丸中西洋参的含量测定。
Objecitve： To establish a method to determine the content of American ginseng in Compound Zaofan Pills. Methods： HPLC was used to determine the content of ginsenoside Rg1 , Re and Rb1 of the American ginseng. Results ： This method had good lin earity in the range of 0. 63 - 5.06 μg（ r = 0. 999 9 ）, and the average recovery was 101.12% with RSD of 2. 14% for ginsenoside Rg1. It had good linearity in the range of 1.05 N 8.4μg（ r = 0. 999 8） , and the average recovery was 100. 71% with RSD of 1.57% for ginsenoside Re. It had good linearity in the range of 2.47 - 19. 74μg（ r=0.9997）, and the average recovery was 97.22% with RSD of 1.92% for ginsenoside Rbl. Conclusion： The method was shown to be convenient, accurate with good repeatability, so it was suitable to determine the content of American ginseng in Compound Zaofan Pills.
出处
《中国药品标准》
CAS
2011年第2期94-98,共5页
Drug Standards of China
