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某院2009至2010年167例抗菌药物不良反应报告分析 被引量:5

ADR Cases Report of a Hospital in 2009-2010:An Analysis of 167 Cases
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摘要 目的分析焦作市第四人民医院抗菌药物不良反应的特点,为临床合理用药提供参考。方法对收集到的167例抗菌药物不良反应报告,按患者性别、年龄比例、引发ADR的抗菌药品种类、给药途径、ADR损害类型及临床表现等进行统计分析。结果引起ADR的抗菌药物涉及11类36个品种。167例ADR中,头孢菌素类居首位,其次是喹诺酮类和青霉素类;静脉给药引发的ADR为82.63%;ADR的临床表现为皮肤及附件损害最为常见,其次是消化系统和神经系统等。结论临床应加强抗菌药物的合理使用及ADR监测报告工作,推动临床合理用药。 Objective To study the characteristics of ADR induced by antimicrobial drugs occurred in Jiaozuo No.4 people's hospital and to promote rational clinical drug use.Methods A total of 167 antimicrobial ADR reports were collected and statistically analyzed in respect of age and sex of patients,route of administrstion,ADR degee,drug category,ADR-involving organs and clinical manifestations and so on.Results 11 categories(36 kinds) of anti-infective drugs were involved in the total 167cases.The ADR were chiefly induced by cephalosporins,followed by quinolones and penicillins;82.63% were induced through intravenous way;which chiefly manifested as lesion of skin and its accessories,followed by the lesions of digestives system and nervous system and so on.Conclusion Clinical should strengthen the rational use of antimicrobial drugs and obtains monitoring report work,promote rational clinical drug use.
作者 牛淑颖
出处 《中国医药指南》 2011年第13期191-192,共2页 Guide of China Medicine
关键词 抗菌药物不良反应 报告 分析 Adverse drug reactions of anti-infective drugs Roport Analysis
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