摘要
目的：了解β-内酰胺类抗生素药物致药品不良反应（ADR）的发生特点，促进临床合理用药。方法：对我院2001年～2005年收集到的442例β-内酰胺类抗生素ADR报告进行回顾性分析。结果：5年间共有961例ADR报告，其中由β-内酰胺类抗生素引起的ADR占总例数的46％；ADR表现以皮肤及附件损伤最为常见，其次为心血管系统、消化系统等。结论：应促进β-内酰胺类抗生素药物的合理使用，并重视ADR的监测工作，以减少或避免ADR的发生。
OBJECTIVE：To study the adverse drug reactions induced by β-laetam antibiotics and to promote rational use of drugs in clinics.METHODS： 442 ADR cases induced by β- laetam antibiotics collected in our hospital during 2001-2005 were analyzed retrospectively.RESULTS：Among the total 961 ADR cases collected in 5 years,46% were induced by β-lactam antibiotics.The most common displays of ADR were the lesion of skin and the appendants, followed by the lesion of cardiovascular system and digestive system etc.CONCLUSION： It is advisable to promote rational use of β-lactam antibiotics and strengthen ADR monitoring so as to decrease or avoid the occurrence of ADR.
出处
《中国药房》
CAS
CSCD
北大核心
2006年第7期528-529,共2页
China Pharmacy
关键词
Β-内酰胺
抗生素
药品不良反应
合理用药
分析
β-lactam
Antibiotics
Adverse drug reaction
Rational administration
Analysis
