摘要
目的:探讨苯接触和慢性苯中毒患者外周血淋巴细胞亚群及T细胞水平的变化。方法:选取收治的慢性苯中毒患者16例和苯接触生产者20例,测定外周血淋巴细胞亚群分布和T细胞水平变化,探讨慢性苯中毒和长期低剂量苯接触对患者机体免疫系统造成的影响。结果:苯接触生产者与慢性苯中毒患者的总T细胞比例显著低于对照组,CD8T细胞比例显著高于对照组,P<0.05,苯接触者和慢性苯中毒患者外周血CD4T细胞比例、B细胞比例以及NK细胞比例,与对照组相比均呈逐渐降低趋势,但差异无统计学意义(P>0.05)。结论:早期检测外周血淋巴细胞亚群分布及变化有助于诊断和治疗。
Objective To discuss peripheral blood lymphocyte subgroup and T cellular lever change of chronic benzene poisoning and benzene touching patients.Methods 16 choronic benzene poisoning patients and 20 benzene touching patients were selected to analyze peripheral blood lymphocyte subgroup and T cellular lever change.Results Total T cell in benzene touching patients were significantly lower than that in chronic benzene poisoing peatients,and no obvious alternation in CD4T cell ratio,B cell ratio and NK cell ratio.Conclusion Earlly detecting peripheral blood lymphocyte subgroup and T cellular lever change was benefit for diagnosis and therapy.
出处
《吉林医学》
CAS
2011年第9期1668-1670,共3页
Jilin Medical Journal
关键词
苯接触
慢性苯中毒
淋巴细胞亚群
T细胞
Benzene touching
Chronic benzene poisoning
Peripheral blood lymphocyte subgroup and T cellular lever change
T cell
