摘要
分别采用溶液上药和粉末上药两种工艺，在流化床设备中制备盐酸苯丙醇胺微丸，对制备工艺和微丸质量进行了评价。结果表明，两种工艺的上药率和微丸收率均较高，制备的微丸质量良好。
Phenylpropanolamine hydrochloride pellets were developed in fluid bed by solution layering and powder layering. The pellets were evaluated for physical properties, and process efficiency was evaluated from processing time, assay, and surface finish quality of the pellets. Results showed that good quality product could be achieved by both layering techniques, and yield of pellets was satisfactory.
出处
《中国医药工业杂志》
CAS
CSCD
北大核心
1999年第8期345-348,共4页
Chinese Journal of Pharmaceuticals
关键词
微丸
盐酸苯丙醇胺
上药工艺
流化床
pellets, phenylpropanolamine hydrochloride, drug layering, fluid bed
