摘要
本文应用微量McCoy细胞培养法,检测了蒲公英等八味清热中药的体外抗衣原体活性,结果表明它们均有不同程度体外抗泌尿生殖过沙眼衣原体的活性,其MIC值从0.49~15.63mg/ml;随着中药浓度的升高,细胞内包涵体的体积和数量减少,最后消失。未见八味中药对McCoy细胞毒性作用。
In order to screen the susceptibilities of urogenital chlamydia trachomatis (CT) to 8 kinds of traditional Chinese medicine by microculture technigue of McCoy cell in Vitro.The results showed that 8 kinds of Chinese medicines all had activities against urogenital CT.Their minimal inhibitory concentrations (MIC)were from 0.49mg/ml to 15.63 mg/ml.The number and the volume of inclusions were reducing gradually, disappeared finally.These traditional Chinese medicines hadn' t any action of cyto-toricity to McCoy cell.The result of this study will be useful for the further study.
出处
《中药材》
CAS
CSCD
1999年第8期414-415,共2页
Journal of Chinese Medicinal Materials
关键词
沙眼衣原体
中药
药敏试验
泌尿生殖道感染
Chlamydia trachomatis
Nongonoccocal urethritis
Traditional Chinese medicine
Drug susceptibility test