摘要
为了探讨中草药对解脲支原体的抗菌作用,我们应用微量稀释法测定了156种中草药对14株解脲支原体国际标准株(每型各1株)的体外抑制效应。结果表明,解脲支原体对黄柏、白芷、地肤子和大黄等有较高的敏感性。其 MIC_(90)≤7.81mg/ml 生药;对甘草、板兰根、黄莲、穿心莲和鱼腥草等敏感性次之,其 MIC_(90)为15.63～62.5mg/ml 生药;对苦楝皮和益母草等敏感性再次之,其 MIC_(90)为62.5～250mg/ml 生药;对黄芩、旱莲草和车前草等,在较高的浓度(15.63～250mg/ml 生药)时,也有少数解脲支原体株敏感;对其余141种中草药不敏感;其 MIC_(90)>250mg/ml 生药。因此,中药在解脲支原体感染的防治上具有重要价值。
In order to study the antibacterial activity of Chinese medicinal herbs to Ureaplasma ure- alyticum(Uu),we examined the inhibitory effect of 156 Chinese medicinal herbs to 14 standard strains of Uu by microdilution method in vitro.The results showed that Uu had a higher sensitivity to Cortex phellodendri,Radix angelicae dahuricae,Fructus kochiae,Radix et rhizoma rhei(MIC_(90)≤7.81mg of dried medicinal herbs/ml);a moderate sensitivity to Radix glycyrrrhizae,Radix isatidis,Rhizoma cop- tidis,Herba andrographitis,Herba houttuyniae(15.63≤MIC_(90)≤62.5);a lower sensitivity to Cortex meliae,Herba leonuri(62.5<MIC_(90)≤250);a certain sensitivity to Radix scutellariae,Herba ecliptae, Herba plantaginis at higher concentration(15.6≤MIC_(90)<250);not sensitive to other 141 Chinese medieinal herbs(MIC_(90)>250).It is our opinion that Chinese medicinal herbs are of momentous signfi- cance in the treatment of Uu infection.
出处
《中华皮肤科杂志》
CAS
CSCD
北大核心
1996年第5期349-351,共3页
Chinese Journal of Dermatology
