摘要
前列腺癌(prostatecancerPC)是欧美国家男性发病率最高的恶性肿瘤,近年来其在我国的发病率也逐年升高。雄激素在PC的发生、发展过程中扮演着重要的角色,所以内分泌治疗一直是前列腺癌研究领域的重点,但是其可能诱发激素非依赖型PC这也是临床医学面临的一大问题。本文就前列腺癌内分泌治疗的分类、作用机制、用药策略及临床效果等作一综述。
Prostate cancer（PC） is the most common malignancy of male in Europe and American.The incidence increased in recent years in our country.Steroid hormones play an important role in occurrence and development of prostate cancer,so endocrine therapy for prostate cancer has been the focus in this field.It may induce the hormone refractory prostate cancer,which is one of the major difficul-ties of clinical medicine.Classification,mechanism,administration strategy and clinical effects of endocrine therapy on prostate cancer are reviewed in this article.
出处
《现代生物医学进展》
CAS
2011年第2期371-374,共4页
Progress in Modern Biomedicine
关键词
前列腺癌
激素抵抗
激素依赖
内分泌治疗
prostate cancer
hormone refractory
hormone dependent
endocrine therapy
