摘要
目的观察前列腺癌患者行雄激素阻断治疗后加服中药与否对患者生存状况和疾病进展的影响。方法将295例行雄激素阻断治疗的前列腺癌患者随机分为加服中药组(n=148)和单纯西药组(n=147),随访观察两组的总体生存率,前列腺癌和非前列腺癌死亡率,病情进展(激素抵抗)出现时间。结果经过中位时间为4.7年的随访,死亡68人(23.1%),其中加服中药组死亡32人(21.6%),单纯西药组死亡36人(24.5%)。两组在总的生存率和死亡原因方面未有差异(P>0.05),而在激素抵抗征象发生率方面加服中药组少于单纯西药组,差异有显著性(P<0.05)。结论益气养阴法对雄激素阻断治疗的前列腺癌患者有一定的辅助疗效。
Objective To observe the effect of Qi-Enriching and Yin-Nourishing therapy combined with androgen deprivation on the living conditions and disease progression of the prostate cancer patients. Methods Total of 295 patients with prostate cancer who underwent routine androgen deprivation therapy were randomly divided into the combined T.C.M. group （n = 148） and the western medicine group （n = 147）. All the treated patients were followed up and overall survival, prostate cancer and non-prostate cancer mortality, the timing of disease progression （hormone refractory） were analyzed. Results After a median time of 4.7 year follow-up, 68 patients died （23.1%） including 32 patients （21.6%） in the T.CM. group and 36 patients （24.5%） in the western medicine group. No significant difference in overall survival rate and causes of death were found between two groups （P〉0.05）. The patients in the combined T. C.M. group had less incidence of hormone refractory symptoms in comparison with that of the western medicine group （P 〈0.05）. Conclusion Qi-enriching and Yin-nourishing therapy had a supplementary effect for prostate cancer patients who underwent androgen deprivation.
出处
《中国男科学杂志》
CAS
CSCD
2010年第6期44-46,53,共4页
Chinese Journal of Andrology
关键词
前列腺肿瘤
益气养阴
prostatic neoplasms
reinforcing qi nourishing yin
