摘要
目的 了解心血管病医院2006—2009年细菌的分布及耐药情况，为医院感染的控制提供依据。方法对医院2006—2009年培养的4483株细菌耐药性进行回顾性分析。结果医院分离病原菌以革兰阴性杆菌为主，占分离病原菌的73．5％；革兰阳性球菌占26．5％；革兰阴性杆菌以肺炎克雷伯菌、铜绿假单胞菌为主，对头孢哌酮／舒巴坦、哌拉西林／他唑巴坦、阿米卡星耐药率低，耐约率分别为1．4％～32．7％、0～32．5％、2．5％～13．0％；铜绿假单胞菌对亚胺培南耐药率有增高趋势；单兰阳性球菌中，以耐甲氧西林凝固酶阴性葡萄球菌为主，未出现耐万古霉素肠球菌。结论加强细菌耐药检测，合理使用抗菌药物，对减少医院感染的发生和耐药菌株产生有重要意义。
OBJECTIVE To analyze the distribution and Drug resistance of pathogens in cardiovascular hospital during 2006- 2009, providing suggestion for clinical treatment. METHODS The drug resistance of 4483 strains of cultured pathogens during 2006-2009 was retrospectively analyzed. RESULTS The pathogens mainly consisted of Gram-negative bacilli（73.5 % ）, followed by Gram positive cocci （26.5 % ）. The Klebsiella pneumoniae and Pseud- omonas aeruginosa were the two major bacterial Gram-negative bacilli, which showed low drug resistance to cefoperazone/suIbactam, piperacillin/tazobactam and amikacin （the resistance rates were 1.4%- 32.7%, 0-32.5% and 2.5%-13% , respectively）. The drug resistant rate of P. aeruginosa to imipem was in an upward tendency. Methicillin-resistant Coagulase negative Staphylococcus （MRCNS） was dominant in the Gram-positive cocci. No vancomycin-resistant Enterococcus was found. CONCLUSION Strengthening the monitoring of the drug resistance and the reasonable use of antibiotics, it can is significantly reduce the nosocomiai infections and the occurrence of drug resistant strains.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2011年第5期969-971,共3页
Chinese Journal of Nosocomiology
关键词
细菌
耐药性
抗菌药物
Bacteria
Drug resistance
Antibiotics
