摘要
目的探讨医院大肠埃希菌(ECO)的感染现状和耐药性,为临床医师治疗感染性疾病提供用药依据。方法严格按照《全国临床检验操作规程》,采用常规方法进行ECO培养鉴定;采用K-B法进行药物敏感试验。结果 216株大肠埃希菌对常用抗菌药物均产生了一定的耐药性,其中对氨苄西林耐药率最高,达92.6%,对亚胺培南敏感率为100.0%;产超广谱β-内酰胺酶(ESBLs)ECO检出率为38.4%。结论医院应加强合理使用抗菌药物管理,严格控制耐药菌的产生和流行。
OBJECTIVE To approach the infection status and drug-resistance in Escherichia coli to provide the scientific evidence for clinical treatment of infective deseases.METHODS According to the National Clinical Laboratory Operation Rule,ECO was cultured and identified by routine method.Drug susceptibility testing was performed by K-B method.RESULTS Certain drug-resistance to commonly used antibiotics occurred in 216 isolates of ECO.The resistance rate to ampicillin （92.6%） was the highest.The sensitivity rate to imipenem was 100.0%.The detection rate of extended spectrum β-lactamase （ESBLs） producing ECO was 38.4%.CONCLUSION The management of antibiotic use and control of the occurrence and prevalence of drug-resistant bacteria should be strengthened.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2010年第16期2515-2516,共2页
Chinese Journal of Nosocomiology
关键词
大肠埃希菌
耐药性
超广谱Β-内酰胺酶
Escherichia coli
Drug-resistance
Extended spectrum β-lactamases
