摘要
目的研究冬青科冬青属植物枸骨Ilex cornuta根中的化学成分。方法运用硅胶、Sephadex LH-20柱色谱对枸骨根中的化学成分进行分离,通过理化常数、质谱和核磁技术鉴定化合物。结果从枸骨根中分离并鉴定了11个化合物,分别为β-谷甾醇(1)、羽扇豆醇(2)、白桦酸(3)、常春藤皂苷元(4)、3β-乙酰基-28-羟基-乌苏醇(5)、乌苏酸(6)、19α-羟基乌苏酸(7)、3β-乙酰基-乌苏酸(8)、23-羟基-乌苏甲酯(9)、庚酸(10)、β-胡萝卜苷(11)。结论化合物4、5、8、9为首次从该属植物中分离得到。化合物3为首次从该植物中分离得到。
Objective To study the chemical constituents of the roots of Ilex cornuta.Methods The compounds were isolated and purified by silica gel,Sephadex LH-20,medium pressure column chromatography,and semi-preparative liquid chromatography,and their structures were elucidated by chemical properties and spectroscop analyses.Results Eight compounds were isolated and their structures were identified to be β-sitosterol（1）,lupeol（2）,betulonic acid（3）,hede-ragenin（4）,3β-acetoxy-28-hydroxyurs-12-ene（5）,ursolic acid（6）,19α-hydroxy ursolic acid（7）,3β-acetoxy-ursolic acid（8）,23-hydroxyl-methyl ursolate（9）,heptanoic acid（10）,β-daucosterol（11）.Conclusion Compounds 4,5,8,and 9 are obtained from this genus for the first time,and compound 3 is obtained from this plant for the first time.
出处
《中草药》
CAS
CSCD
北大核心
2011年第2期234-236,共3页
Chinese Traditional and Herbal Drugs
基金
苏州大学青年基金项目(2008)
苏州大学大学生创新试验计划项目资助(2009DC03092)
