摘要
目的:观察腹腔镜术后辅助GnRH-a治疗子宫内膜异位症的临床疗效,探讨治疗子宫内膜异位症的最佳治疗方案。方法:选择采用腹腔镜治疗术后确诊为子宫内膜异位症患者126例,按照自愿的原则分为对照组与观察组,对照组53例术后未采用辅助治疗,观察组73例术后辅助GnRH-a治疗12个月后比较两组患者治疗前后生殖激素水平变化、总主观症状评分及临床疗效。结果:治疗12个月后,两组患者治疗后生殖激素水平、总主观症状评分及临床疗效方面比较差异有统计学意义(P<0.05)。结论:外科治疗子宫内膜异位症时应术后辅助GnRH-a治疗,可提高临床疗效、减少复发。
Objective：To observe the clinical efficacy of gonadotropin releasing hormone agonist（GnRH-a） in treatment of endometriosis after laparoscopic surgery,explore the optimum therapeutic scheme of endometriosis.Methods：126 cases diagnosed as endometriosis definitely after laparoscopic surgery were selected and divided into control group and observation group according to the principle of voluntariness,53 cases in control group did not received adjuvant therapy,73 cases in observation group were treated with GnRH-a for 12 months after laparoscopic surgery,then the changes of reproductive hormones levels,the total subjective symptoms scores and clinical efficacies in the two groups were compared.Results：After treatment for 12 months,there was significant difference in reproductive hormones levels,the total subjective symptoms score and clinical efficacy between the two groups（P〈0.05）.Conclusion：Laparoscopic surgery combined with GnRH-a is effective,which may reduce the recurrence rate of endometriosis.
出处
《中国妇幼保健》
CAS
北大核心
2011年第4期620-622,共3页
Maternal and Child Health Care of China
