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腹腔镜卵巢子宫内膜异位囊肿术后GnRH联合反添加治疗分析 被引量:11

Gonadtropin-releasing hormone agonist combined with addback therapy in the treatment of endometriosis
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摘要 目的:探讨子宫内膜异位囊肿患者行腹腔镜手术后服用促性腺激素激动剂联合反添加治疗的临床治疗效果及应用价值。方法:选择我院腹腔镜手术治疗的子宫内膜异位囊肿患者116例,随机分为观察组和对照组,两组均行腹腔镜手术治疗,术后对照组给予亮丙瑞林治疗,观察组在对照组基础上联合使用反向添加治疗,观察两组患者性激素水平、疼痛程度评分变化及复发情况。结果:观察组在改善性激素水平和疼痛状况评分情况均优于对照组,经统计学分析,差异有统计学意义(P<0.05)。观察组患者复发率低于对照组,经统计学分析,差异有统计学意义(P<0.05)。结论:子宫内膜异位囊肿患者行腹腔镜手术后服用促性腺激素激动剂联合反添加治疗安全有效,降低复发率,减轻患者疼痛症状评分,对内分泌代谢影响较小,值得在临床上大力推广使用。 Objectives: To explore the clinical efficacy of taking gonadotrophin- releasing hormone agonist combined with addback therapy for patients with endometriosis after laparoseopic surgery. Method: 116 patients were selected who received lap- aroscopic surgical treatment, and they were randomly divided into observation group and control group. In both groups, the pa- tients were operated with laparoscopic surgery. The patients in the control group were given postoperative light gonadorelin treat- ment while the patients in the observation group received reverse adding treatment. And the indicators of sex hormone level and the pain degree score were recorded and compared in the two groups. Results: In the observation group, the sex hormone level improved, and the pain score improvement was superior to that of the control group, with statistically significant difference (P 〈 0. 05). In the observation group, the patients' relapse rate was lower than that in the control group, with statistically significant difference ( P 〈 0. 05 ). Conclusion: For Endometriosis cyst patients, using gonadotrophin - releasing hormone agonist joint add - on therapy after laparoscopic surgery is safe and effective, which can reduce the recurrence rate and the patients pain symptom scores, with less effect on endocrine metabolism.
作者 吴芸
出处 《中国性科学》 2013年第10期20-22,共3页 Chinese Journal of Human Sexuality
关键词 卵巢子宫内膜异位囊肿 GNRH 反向添加治疗 Endometriosis Gonadtropin- Releasing Hormone Addback Therapy
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