摘要
目的:为寻找更有效使用玻璃酸钠(SH)与复方倍他米松关节腔内注射补充治疗膝关节骨性关节炎(OA)的方法。方法:2009年3月-2010年3月治疗160例膝骨性关节炎引起的轻度到重度疼痛的患者,随机分成2组。治疗组每周进行膝关节内注射玻璃酸钠1次,共5周,并在前3周同时注射复方倍他米松。对照组每周进行膝关节内注射玻璃酸钠1次,共5周。治疗结束后随访半年。结果:治疗组的显效率46.3%,有效率为30.0%,对照组显效率31.3%,有效率为15.0%,2组差异有显著性(P<0.05)。结论:关节腔内注射玻璃酸钠和复方倍他米松治疗膝关节骨性关节炎疼痛能快速、持久缓解疼痛,改善膝关节功能,同时没有额外的并发症。
OBJECTIVE To explore the effect of intraartieular injection of sodium hyaluronate（SH） anddiprospan on knee osteoarthritis （OA）. METHODS Treated 160 cases with OA and intra-articular injection of diprospan at 1 mL everyweek for3 weeks, with disappearance ofpain and positive result in stretching patellar test as standard for drug withdrawal. Then treated patients with injection of SH at 2 mL every week for 5 weeks. RESULTS There was no significant difference between the test group and the control group（P〈0.05）. CONCLUSION Eliminating inflammation by diprospan and protecting articular surface with SH is valuable choice in treating patients with OA.
出处
《中国医院药学杂志》
CAS
CSCD
北大核心
2011年第4期311-313,共3页
Chinese Journal of Hospital Pharmacy
关键词
骨性关节炎
玻璃酸钠
治疗
knee
osteoarthritis
sodium hyaluronate
treatment
