摘要
本文用邻片免疫组织化学双标记方法，对文昌鱼脑泡中ＧｎＲＨ 和５ＨＴ 神经自调节及相互调节的形态学基础进行了研究。结果发现，ＧｎＲＨ 阳性神经元含有ＧｎＲＨ 受体和５ＨＴ 受体；５ＨＴ 阳性神经元含有５ＨＴ 受体和ＧｎＲＨ 受体。提示，文昌鱼脑泡中ＧｎＲＨ 和５ＨＴ 神经元存在类似哺乳动物下丘脑的自调节和相互调节机制。
Morphological basis for autoregulation and mutual regulation of GnRH and 5 HT in the cerebral vesicle of Amphioxus was studied using immunohistochemical double labeling method. The results indicated that the GnRH immunoreactive neurons contained both GnRH receptors and 5 HT receptors, meantime, 5 HT immunoreactive neurons contained both 5 HT receptors and GnRH receptors. These results illustrate that the GnRH and 5 HT neurons in the cerebral vesicle of Amphioxus may possess autoregulation or mutual regulation mechanism which was similar to those of the GnRH and 5 HT neurons in mammal hypothalamus. (Figures 1～8 on plate 33)
出处
《神经解剖学杂志》
CAS
CSCD
北大核心
1999年第2期182-184,共3页
Chinese Journal of Neuroanatomy
关键词
GNRH
5-羟色胺
受体
文昌鱼
脑泡
调节
gonodotropin releasing hormone, 5 HT, receptor, immunohistochemisty, cerebral vesicle of Amphioxus
