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丙二酰辅酶A轴——缺血性心脏病治疗的新靶点 被引量:2

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摘要 心血管疾病是人类疾病死亡和残疾的主要原因,其中缺血性心脏病已成为心血管疾病的主要负担。目前缺血性心脏病的治疗主要包括:改善心脏血供、增加氧气供应以及减少心脏的需氧。尽管近来治疗有新的进展,但缺血性心脏病仍是一个主要健康问题。因此,新的治疗策略是必需的,而优化心肌能量代谢可使心脏更高效地产生能量,并更有效降低与缺血/再灌注相关的酸中毒程度。本文对近年来通过操控丙二酰辅酶A轴优化心肌能量代谢进行综述。
出处 《安徽医药》 CAS 2011年第1期105-107,共3页 Anhui Medical and Pharmaceutical Journal
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