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精神病患者血清SIL-2R水平的研究

The study of the serum SIL2R in psychotic patients
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摘要 目的探讨SIL-2R在精神病患者血清中水平及临床意义。方法用ELISA检测了192例精神病患者血清SIL-2R含量。结果精神病患者血清SIL-2R水平明显高于对照组(P<0.01);精神病患者男女之间血清SIL-2R水平无差异(P>0.05);阳性家族史与阴性家族史患者SIL-2R均高于对照组(P<0.01),经精神药物治疗痊愈的51例患者血清SIL-2R水平减低,与对照组无差异(P>0.05)。结论检测血清SIL-2R水平反映精神病患者免疫状况和病情变化。 Objective To investigate the serum SIL2R level in psychotic patients and its clinical relevance. Method The levels of serum SIL2R of 192 psychotic patients were measured with ELISA. Results The levels of serum SIL2R of psychotics were higher than that of control(P<0.01); the level of serum SIL2R has no different between male and female patients(P>0.05).The patients with positive family history and those with negative family history all had higher levels of serum SIL2R than control group (P<0.01).After treated with psychotherapeutic drugs,51 recovered patients had lowered levels of serum SIL2R without difference from control group (P>0.05). Conclusion The levels of SIL2R can be a marker to reflect the immune status and the changes of the disease in the disease in psychotic patients.
作者 杜翠瑛
出处 《中国行为医学科学》 CSCD 1999年第2期132-133,共2页 Chinese Journal of Behavioral Medical Science
关键词 精神病 白细胞介素2 受体 PsychoticSIL2R
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参考文献4

  • 1中华医学会精神科学会.中国精神疾病分类方案和诊断标准(CCMD-2-R)[M].南京:东南大学出版社,1994.56-72.
  • 2季舜玉,毛建明.细胞因子与精神分裂症关系的实验研究[J].临床精神医学杂志,1997,7(2):76-77. 被引量:9
  • 3季舜玉,临床精神医学杂志,1997年,1期,76页
  • 4中华医学会精神科学会,中国精神疾病分类方案与诊断标准,1994年,56页

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