摘要
目的探讨各种肾病患者血清免疫球蛋白及补体检测的意义。方法采用速率散射浊度法检测急性肾炎(AN)、慢性肾炎(CN)、肾病综合征(NS)、尿毒症(UR)患者及健康对照(normal)者血清免疫球蛋白(IgG、IgA、IgM)和补体(C3、C4)水平。结果 (1)各种肾病组IgG均有不同程度的降低,各项指标降低程度各组依次为:normal>AN>CN>NS>UR;(2)AN患者血清IgA明显高于其他肾病组;(3)UR患者血清补体C3水平明显低于其他各组,差异有统计学意义(P<0.05)。结论检测血清中免疫球蛋白和补体水平,不仅有利于各种肾病的鉴别诊断,还对临床上肾病的治疗和预后评估具有一定的参考意义。
Objective To explore the effects of immunoglobulins and complements in kidney diseases. Methods Nephelometry was used to determinate the serum level of immunoglobulin（IgG, IgA, IgM） and complements（C3, C4 ）in the patients with acute nephritis（AN）, chronic nephritis（CN）, nephrotie syndrome（NS） and uraemia（UP,）. Resuits （1）IgG was decreased in each group of kidney diseases：normal-〉AN〉CN〉NS〉UR;（2）IgA in AN group was higher than that in other groups; （3）C3 in UR group was lower than that in other groups（P〈0.05）. Conclusion Serum levers of IgG,IgA,IgM,C3 and C4 can not only be used to differentiate kidney diseases, also are helpful to therapy and the prognostic diagnosis of kidney diseases.
出处
《检验医学与临床》
CAS
2011年第1期4-5,共2页
Laboratory Medicine and Clinic
基金
南京军区医学科技创新经费资助项目(08MA076)
