摘要
对雌性大鼠、小鼠的生殖系统,人的子宫内膜与蜕膜进行了3-β-羟基甾体脱氢酶(3-β-HSDH)和脂类的组织化学研究。结果表明:在大鼠和小鼠的卵巢内,颗粒黄体细胞和膜黄体细胞3-β-HSDH呈强阳性反应,卵泡膜内层细胞与间质细胞呈中等程度阳性反应;大鼠与小鼠子宫内膜的表面上皮与腺上皮呈阳性反应;人早孕期蜕膜中的子宫腺上皮细胞与大蜕膜细胞呈阳性反应:在大鼠与小鼠的输卵中偶尔见到阳性反应物质;在人的子宫内膜中,没有见到阳性反应。本研究证明,雌性大鼠和小鼠除卵巢有分泌甾体素的功能外,子宫也有分泌甾体激素的功能。人早孕期蜕膜组织中的子宫腺与大蜕膜细胞都能分泌甾体激素。
If the tissue or organ have 3-β-hydroxy steroid dehydrogenase (3-β-HSDH), they can synthesize the steroid hormone. According to that idea, we have studied the distribution of 3-α-HSDH in the female reproductive system of rats and mice, human endometrium and decidua with histochemical techniques. The results as follows: 1. The granular lutein cells and the theca lutein cells have showed a strong positive reaction. Theca interna cells and metrial gland cells were middle positive staining in the ovary of rats and mice. 2. The glandular epithelium and the surperficial epithelium showed moderate positive reaction. 3. The glandular epithelium and the big decidual cells of human decidua were moderate positive. 4. We did not look for a positive endometrial cells in human endometrium. The present study have been idenlified that the uterus of rats and mice, and the endomitrial cpitheliums and big cells of women＇s decidua possessed the funetion to secrete Steroid hormones. We proposed that the uterus of rat and mice and human decidua may be a endocrine organ.
基金
国家计划生育委员会资助
