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围绝经期综合征中西医临床研究进展 被引量:35

Progress on clinical research of traditional Chinese medicine and western medicine for perimenopausal syndrome
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摘要 本综述回顾了围绝经期综合征的中医西医病因病机、治疗现状,并展望了该病的可能研究方向。特殊的身体时期下丘脑—垂体—卵巢这个内分泌轴发生变化,导致一系列植物神经紊乱为主的症状。中医认为本病肾虚为本,同时肝气郁结、痰瘀内生等密切相关。西医治疗以激素替代疗法为主,大豆异黄酮治疗以及心理治疗也取得一定的研究进展。中医以辨证治疗为主,专方专药、针灸疗法也广泛应用于临床。中医治疗可能有一定的治疗效果,但是低质量的随机对照研究充斥,尚无充分的循证医学证据肯定其疗效。严格的中药治疗围绝经期综合征的随机双盲对照试验是未来的研究重点。 This article reviews the TCM and western medicine pathogenesis and treatment about perimenopausal syndrome, and discusses the possible research direction about it. In Special body period, the endocrine shaft of hypothalamus-pituitary-ovarian changes, resulting to a series of plant nerve disorder symptoms mainly. Doctors of traditional Chinese medicine think that the basic pathogenesis of this disease is kidney deficiency, and at the same time, liver qi depression and phlegm and blood stasis endogenous are also closely related. In Western medicine, hormone replacement therapy is most common treatment. There is also some research progress on soybean isofiavone therapy and psychological treatment. In traditional Chinese medicine ,Syndrome differentiation and treatment is the priority. Special formula and medicine, and acupuncture treatment are also widely used in clinical. Traditional Chinese medicine treatment may have a cer- tain therapeutic effect. But there are too many low quality of randomized controlled trials, and there is no full evidence-based medical evidence to verify TCM' s curative effect. In traditional Chinese medicine treatment of perimenopausal syndrome, strict double-blind randomized controlled trial is an important research direction in the future.
作者 王利芬
出处 《环球中医药》 CAS 2013年第2期151-155,共5页 Global Traditional Chinese Medicine
关键词 围绝经期综合征 激素替代疗法 辨证论治 大豆异黄酮 肾虚 综述 Perimenopausal syndrome Hormone replacement therapy Syndrome differentiation and treatment Soybean isoflavones Kidney deficiency Review
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