摘要
目的对化妆品质控样品中砷的均匀性及稳定性进行检验。方法采用原子荧光光度法测定化妆品质控样品中的砷含量,并采用t检验和F检验联合技术进行均匀性检验,通过比较测定结果的相对标准偏差和测量方法的扩展不确定度评价稳定性。结果 3个批次质控样品中砷元素瓶内与瓶间各组测定结果的均值与方差不存在显著性差异。在有效期内,不同时间间隔内砷测定结果之间的相对标准偏差小于测量方法的扩展不确定度。结论所研制的化妆品质控样品中的砷符合均匀性和稳定性要求。
Objective To study the homogeneity and stability of arsenic in quality controlling cosmetic samples.Methods Arsenic was determined by atomic fluorescence spectrophotometric method.The t-test and Ftest were used to evaluate the significant difference of the within-bottle and between-bottle results with three batches.The RSDs of arsenic obtained in different time were compared with the relative expanding uncertainties to evaluate the stability.Results Average and variance of within-bottle and between-bottle results of arsenic were not different significantly.The RSDs of Arsenic were less than the relative expanding uncertainties.Conclusion Quality controlling cosmetic samples containing arsenic were considered homogeneous and stable.
出处
《卫生研究》
CAS
CSCD
北大核心
2010年第6期774-776,共3页
Journal of Hygiene Research
关键词
化妆品质控样品
砷
均匀性
稳定性
quality controlling cosmetic samples
arsenic
homogeneity
stability
