摘要
应用处死的青春双歧杆菌ＤＭ８５０４菌株皮下免疫荷瘤小鼠，按Ｇｒｉｅｓ反应原理测定一氧化氮（ＮＯ）的含量。结果表明，双歧杆菌能提高荷瘤小鼠体内ＮＯ的含量，较对照组显著升高，肿瘤组织的坏死程度在处理组与对照组之间也具有显著性差异。提示：在双歧杆菌抗肿瘤作用中，除ＴＮＦ—α外，ＮＯ也发挥重要作用。
In this study,heat-killed cells of Bifidobacterium adolescentis DM8504 strain was injected subcutaneously in HCa-F 25 /16A 3-F tamor-bearing BALB/C mice The level of production of nitric odide (NO) was determined by Griess reaction The result indicated that NO production and extent of tumor necrosis were augmented in tumor-bearing mice treated with B adolescentis Dm8504 strain compared with control group It was suggested that NO could play an important role except TNF-2 in antitumor activity of B adolescentis Dm8504 strain
出处
《中国微生态学杂志》
CAS
CSCD
1999年第2期70-72,共3页
Chinese Journal of Microecology
关键词
青春双歧杆菌
抗肿瘤作用
NO诱生
Bifidobacterium\ adolescentis\ Nitric\ oside\ Antitumor\ actioity
