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胃癌手术患者预后的多因素分析 被引量:29

Multivariate prognostic factors analysis of patients with gastric cancer undergoing operation
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摘要 目的探讨影响胃癌手术患者预后的相关因素。方法应用单因素和多因素的分析方法,回顾性分析1990年1月至2001年12月有完整临床资料和随访资料的887例胃癌患者的临床资料。结果胃癌患者总的1年生存率为79.63%,3年生存率为49.29%,5年生存率为43.40%。单因素分析结果显示肿瘤部位,TNM分期,病理分型,手术方式,化疗方法与患者的预后具有相关性。应用COX回归模型分析显示TNM分期,病理分型,手术方式,化疗方法是影响胃癌患者手术预后的相关因素。结论 TNM分期,病理分型,手术方式,化疗方法是影响胃癌手术患者预后的重要指标。 Objective To analyze the related factors affecting the prognosis of gastric cancer patients undergoing operation.Methods The clinical characteristics and follow up data of 887 patients with gastric cancer treated from January 1990 to December 2001 in our hospital were retrospectively analyzed by univariate and multivariate methods.Results Of the 887 cases,the overall 1-,3-and 5-year survival rate was 79.63%,49.29% and 43.40%,respectively.In the univariate analysis,tumor location,TNM stage,pathological type,operative method,and chemotherapy were related to the prognosis of patients with gastric cancer.Multivariate Cox model analysis showed that TNM stage,pathological type,operative method,and chemotherapy were the related factors for patients with gastric cancer.Conclusions TNM stage,pathological type,operative method,and chemotherapy are important prognostic factors for patieuts with gastric cancer undergoing operation.
出处 《中国普通外科杂志》 CAS CSCD 北大核心 2010年第10期1061-1064,共4页 China Journal of General Surgery
关键词 胃癌 预后 多因素分析 Gastric Cancer Prognosis Multivariate Analysis
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参考文献4

  • 1杨维良.进展期胃癌的治疗[J].中国普通外科杂志,2001,10(3):193-196. 被引量:23
  • 2邹寿椿,裘华森,张成武,施敦,赵大建,姜蔚,张静霞,陶厚权.胃癌围手术期三联序贯疗法的临床研究和随访[J].中华消化杂志,1999,19(3):210-211. 被引量:17
  • 3Yoshitaka Yamamura,Toshifusa Nakajima,Keiichiro Ohta,Atsushi Nashimoto,Kuniyoshi Arai,Masahiro Hiratsuka,Mitsuru Sasako,Yasuhiro Kodera,Masashi Goto. Determining prognostic factors for gastric cancer using the regression tree method[J] 2002,Gastric Cancer(4):0201~0207
  • 4Jonathan B. Koea MD,Martin S. Karpeh MD,Murray F. Brennan MD. Gastric Cancer in Young Patients: Demographic, Clinicopathological, and Prognostic Factors in 92 Patients[J] 2000,Annals of Surgical Oncology(5):346~351

二级参考文献1

  • 1Wu C C,J Am Coll Surg,1997年,184卷,611页

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