摘要
目的:探讨影响胃癌患者术后生存的独立因素。方法:对1995年10月至1999年4月814例手术治疗的胃癌患者进行了单因素及多因素COX回归分析。结果:全组总的1年生存率为71.87%,3年生存率为45.33%,5年生存率为40.05%。经单因素和多因素分析Borrmann大体分型、病理类型、TNM分期、手术方式、手术根治度是影响胃癌预后的独立因素。结论:胃癌的Borrmann大体分型,病理类型,TNM分期是影响其术后生存的生物学因素;手术是治疗胃癌最有效的手段,根治性切除是使其达到治愈的唯一途径。
Objective： To identify independent prognostic factors after surgical operation on patients with gastric cancer. Methods： A total of 814 patients with gastric cancer, treated surgically from October, 1995 to April, 1999, were studied by univariate and multivariate analysis. Results： Of the 814 cases, the 1-year, 3-year and 5-year overall survival rate was 71.87%, 45.33% and 40.05%, respectively. The univariate and multivariate analysis showed that five type of factors, such as Borrmann types, radical gastrectomy, way of resection, pathological type and TNM staging, were taken as the major independent prognostic factors. Conclusions： To improve the survival rate of gastric cancer, the reasonable plan of gastrecomy should be drawn up and the synthetic treatment around surgery should be performed basing on biological characteristics of each patient with the TNM clinical stage and Borrmann type, etc.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
2006年第7期399-402,共4页
Chinese Journal of Clinical Oncology
关键词
胃癌
外科治疗
预后
COX回归分析
Gastric cancer Surgical procedures Prognosis Cox regression analysis
